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The 44% reduction in histological degeneration scores is a clinically meaningful finding

Sampson CM, Dimet AL, Neelakantan H, Ogunseye KO, Stevenson HL, Hommel JD, Watowich SJ (2021) Combined nicotinamide N -methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice

L'une des principales cibles identifies est la voie de l'oxyde nitrique (NO), o le peptide agit comme modulateur de la synthse de NO via les enzymes NO synthases (NOS)

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Dec 2014;30(12):2471-2481